Rejuran is part of a new generation of skin therapies that focus less on appearance and more on restoring function. Using polynucleotides derived from salmon DNA, this treatment supports the skin’s own repair processes, helping it rebuild what has been worn down by time, stress, or environmental exposure.
Quick Answers About Rejuran Skin Rejuvenation
What is Rejuran and how does it work?
Rejuran is a skin therapy that uses polynucleotides derived from salmon DNA to support skin regeneration. It repairs damaged cells, boosts collagen production, and improves elasticity by working deep within the dermis.
What results can I expect after Rejuran treatments?
Most people notice improved hydration, smoother texture, and stronger elasticity within weeks. Over time, the skin appears firmer, more even, and visibly refreshed.
Is Rejuran available in Hobart?
Yes. Rejuran skin rejuvenation treatments are available at Heart Aesthetics Hobart, where tailored plans are developed to suit your skin’s needs and concerns.
How Rejuran Supports Skin Repair
What makes Rejuran different from traditional skin treatments is its focus on biological repair rather than artificial enhancement. It doesn’t rely on synthetic volume or surface hydration. Instead, it delivers biocompatible polynucleotides naturally derived from salmon DNA into the deeper layers of the skin, where they help restore function at a cellular level.
These polynucleotides are long-chain molecules that the body recognises and responds to. Once delivered into the dermis, they support the repair of damaged cells, encourage collagen regeneration, and improve moisture retention. Over time, this process helps rebuild elasticity, refine texture, and strengthen the skin barrier.
Why Salmon DNA?
Salmon DNA is used in Rejuran because it closely resembles human DNA in structure, making it highly compatible with our tissue. When introduced into the skin, these polynucleotides activate repair mechanisms that typically slow down with age. This includes improving the skin’s ability to heal, maintain hydration, and protect against daily damage.
The treatment works through three main pathways:
-
Repairing cellular damage by activating DNA repair responses
-
Encouraging new cell growth through the regeneration of healthy skin tissue
-
Reinforcing barrier function to protect against environmental stress
Collagen, Texture, and Skin Strength
One of the key outcomes of Rejuran is its ability to stimulate fibroblasts, the cells responsible for producing collagen. As these cells become more active, the structure of the skin begins to shift. Areas that once felt thin, creased, or slack become more resilient, with noticeable changes in firmness and surface texture.
Lines soften gradually as the skin’s framework is rebuilt from within. Rather than stretching or freezing facial movement, Rejuran enhances how your skin responds to stress and recovers from ageing changes.
Calming, Not Just Correcting
Rejuran’s benefits also extend to skin that’s reactive, fragile, or inflamed. Many people notice a reduction in redness, sensitivity, or irritation following a course of treatments. This anti-inflammatory effect can be particularly helpful for those with a damaged barrier, post-acne scarring, or signs of sun stress.
What sets Rejuran apart in clinics across Hobart is its ability to deliver visible results without disrupting how your face looks or feels. It supports natural repair processes that are already built into the skin, just reactivated with the help of science.
What Skin Concerns Can Rejuran Help With?
Rejuran is designed for skin that has become less resilient over time, whether due to aging, environmental stress, or slowed cellular repair. Rather than masking change, it works beneath the surface to support regeneration where the skin has lost structure, balance, or clarity.
In Hobart, many clients turn to Rejuran to soften early lines, improve firmness in the cheeks or jawline, and restore texture in areas affected by past breakouts, acne scarring, or sun exposure. It stimulates collagen, smooths surface irregularities, and helps the skin renew itself gradually, building strength with each session.
The treatment also supports hydration by reinforcing the skin’s natural barrier. This becomes especially important during Tasmania’s cooler months, when dryness and reactivity are more common. Clients often notice their skin holds moisture better, feels calmer, and becomes less prone to irritation after a course of treatments.
Rejuran suits a wide range of skin types and tones. It adapts to oily, dry, or combination skin and is compatible with Fitzpatrick skin types I through VI. Many people choose it when noticing early signs of dullness, thinning, or fatigue, while others use it to support recovery after stress, sun exposure, or inflammation.
What makes Rejuran different in the Hobart market is its focus on restoring function, rather than altering the appearance of your face, by helping your skin respond, heal, and maintain its shape with greater consistency over time.
Which Type of Rejuran Is Right for You?
Rejuran is available in three specialised formulations, each designed to address different skin concerns with targeted application. While they all work by delivering polynucleotides into the skin, the technique and focus area vary depending on what your skin needs most.
Rejuran Healer
Rejuran Healer is the most versatile option. It’s used across the full face and is ideal for those seeking a general improvement in skin tone, elasticity, and strength. This version supports widespread collagen stimulation and is applied through a series of precisely placed, shallow deposits that allow the active ingredients to integrate evenly throughout the skin. Over time, clients notice a reduction in fine lines, better skin texture, and a more uniform, resilient appearance. It suits people who want to target early signs of ageing or simply refresh tired-looking skin without altering their features.
Rejuran S
Rejuran S is tailored specifically for scars. Unlike the full-face approach of Rejuran Healer, this version is used in small, concentrated amounts and is placed directly into areas of old or new scarring. It’s commonly chosen by clients with acne scars or uneven skin from past damage. Rejuran S helps remodel the tissue underneath the scar, promoting collagen growth where it’s been disrupted and improving surface texture over time. While results build gradually, the smoothing effect is often long-lasting.
Rejuran I
Rejuran I focuses on the under-eye region, where skin is especially thin and sensitive. This formulation is applied using a micro-droplet technique to ensure precision without overwhelming delicate tissue. It’s often recommended for people experiencing early creasing, dark circles, or general thinning around the eyes. Rejuran I strengthens the skin barrier in this fragile zone, helping it retain moisture, resist irritation, and recover from environmental stress.
At Heart Aesthetics Hobart, each Rejuran formulation is carefully selected based on how your skin heals, moves, and responds to stress. Treatment plans are customised to target areas that need the most support, whether it’s overall texture, scarring, or delicate zones like the under-eyes. By matching the product to your skin’s function and condition, we help strengthen your natural features without changing their character.
How Results Develop After Rejuran Treatment
Rejuran is not a quick-fix treatment; it’s a structured process that builds progressively. Within the first one to two weeks, many clients notice improved hydration, smoother surface texture, and reduced irritation. Redness and reactivity often settle, leaving the skin feeling calmer and more stable.
By week four, elasticity begins to return. The skin starts to resist creasing more effectively, and fine lines gradually soften. The barrier becomes stronger, and a subtle radiance starts to emerge, especially in areas that previously looked tired or flat.
Between two and three months, deeper shifts occur. Collagen production increases, pores appear smaller, and scars begin to soften. The overall structure of the skin feels firmer and more uniform. These outcomes continue to evolve even after your treatment course is complete.
Most clients undergo three to four sessions spaced three to four weeks apart. Maintenance sessions are typically recommended every six to twelve months to maintain stable results.
Supporting Skin Recovery: Rejuran Aftercare and Safety
What you do after treatment plays a significant role in how well your skin responds. In the hours following your session, it’s important to keep the area clean, cool, and free from friction. Avoid makeup, heavy creams, or sun exposure for the first 24 hours, and give your skin time to settle before reintroducing active products.
For the first 48 hours, skip saunas, exfoliation, and strenuous exercise. Choose gentle cleansers, layer in hydration, and apply SPF 50+ daily. This not only supports your skin’s recovery but also protects the polynucleotides as they begin working within the dermis.
At Heart Aesthetics Hobart, you’ll be given a home care routine suited to your current skin condition. Products containing hyaluronic acid, vitamin C, or peptides may be recommended to complement the regenerative effects of Rejuran and reinforce the skin barrier as it rebuilds.
Most skin types can tolerate Rejuran. Its polynucleotides are highly purified and biocompatible, which means the skin accepts them without triggering irritation or inflammation. Treatments at Heart Aesthetics Hobart are performed under sterile conditions using single-use equipment and clinical protocols that meet Australian safety standards.
Mild redness, swelling, or tiny bumps at the application areas are normal and usually resolve within 24 to 48 hours. These effects are short-lived and can be soothed with a cold compress if needed. Allergic reactions are extremely rare due to the purity of the formulation.
Rejuran is considered a safe and low-risk option for most people. However, as with any cosmetic therapy, potential risks are involved, including delayed healing or individual sensitivity. Rejuran is not recommended during pregnancy while breastfeeding, or if you have active skin infections or certain autoimmune conditions. These factors will be discussed during your consultation to ensure the treatment is suitable for you.
What to Expect During a Rejuran Session in Hobart
Every Rejuran session at Heart Aesthetics Hobart begins with a consultation that examines your skin’s condition, movement, and underlying patterns of change. This isn’t just a checklist; it’s a clinical assessment that shapes your treatment plan.
Once mapped out, your skin is cleansed, photographed, and numbed with a topical cream. Rejuran is then applied using ultra-fine needles at precise depths, delivering the polynucleotides evenly through the dermis. A cooling mask may follow to ease redness and support early healing.
Small, raised bumps or mild redness may appear after treatment. This is expected and typically resolves within 24 to 48 hours. To support recovery, avoid heat, makeup, or vigorous activity during the first two days.
What Does Rejuran Cost in Hobart?
In Hobart, Rejuran pricing ranges between $650 and $1350 per session depending on the formulation used, treatment area, and number of syringes required. Full-face rejuvenation using Rejuran Healer tends to sit at the upper end of this range, while smaller zones, such as the under-eyes or localised scarring, require less product.
Package options offer better value. Most clients complete a course of three to four sessions, with multi-session plans offering 10–20% savings. Maintenance appointments are available at reduced rates to support long-term results.
As with all non-surgical treatments, Rejuran is not covered by private health insurance. However, Heart Aesthetics Hobart provides flexible scheduling and payment options to make your care more accessible.
Frequently Asked Questions About Rejuran Treatments in Hobart
What are the benefits of salmon DNA treatments like Rejuran?
Rejuran supports collagen repair, reduces fine lines, enhances hydration, and strengthens the skin barrier. It offers natural-looking results for tired, ageing, or damaged skin.
How does Rejuran Healer compare to other formulations?
Rejuran Healer is the most versatile option in the range. It’s used across the full face to improve elasticity, fine lines, and general skin quality by encouraging cellular repair.
What is Rejuran I used for?
Rejuran I targets delicate areas such as the under-eyes. It improves tone, reduces fine lines and dark circles, and strengthens fragile skin in the tear trough region.
How many Rejuran sessions will I need?
Most clients benefit from three to four initial sessions spaced three to four weeks apart. Maintenance every six to twelve months can help prolong the results.
Is Rejuran safe to use in Australia?
Yes. Rejuran is widely used across Australia and administered under strict clinical protocols. At Heart Aesthetics Hobart, treatments are performed using regulated medical products in a sterile, professional setting. As with any cosmetic therapy, individual risks are discussed during your consultation to ensure the treatment is appropriate for your skin and health.
Are there any side effects after Rejuran?
Minor swelling, redness, or raised spots at the application points are common and temporary. These usually settle within 24–48 hours. Allergic responses are extremely rare due to the biocompatibility of salmon DNA.
Ready for Stronger, Smoother Skin? Start With Rejuran in Hobart
Whether you’re looking to repair signs of ageing, calm inflammation, or restore texture after breakouts or stress, Rejuran offers a science-backed way to support your skin from within. With each treatment, your complexion becomes stronger, more even, and visibly refreshed, without altering your appearance. It’s a gentle, progressive approach that suits sensitive skin, responds well to local climate stressors, and builds resilience where your skin needs it most. If you’re considering regenerative skin therapy, now is the time to book Rejuran treatment in Hobart and experience what skin renewal can feel like when it’s led by your body, not masked by volume.
References
Heart Aesthetics Hobart always ensures the use of credible, up-to-date references for all our content related to cosmetic treatments in Hobart. We rely on peer-reviewed studies and trusted medical sources to provide accurate information to our local community in Hobart, Tasmania.
Araco A, Araco F, Raichi M. (2023). Clinical efficacy and safety of polynucleotides highly purified technology (PN-HPT®) and cross-linked hyaluronic acid for moderate to severe nasolabial folds: A prospective, randomized, exploratory study. J Cosmet Dermatol, 22(1):146-155. doi: 10.1111/jocd.15064. PMID: 35531796; PMCID: PMC10084116.
https://doi.org/10.1111/jocd.15064
Camilia A, Gadila AP, Dwiputri MF, Arief SFI, Setyadi YP. (2025). The role of Salmon DNA in Skin Regeneration and Anti-Aging. Med Inf Technol, 3(2):79–86. doi: 10.37034/medinftech.v3i2.95.
https://doi.org/10.37034/medinftech.v3i2.95
Ceccarini MR, Ripanti F, Raggi V, Paciaroni A, Petrillo C, Comez L, Donato K, Bertelli M, Beccari T, Valentini L. (2023). Development of Salmon Sperm DNA/Regenerated Silk Bio-Based Films for Biomedical Studies on Human Keratinocyte HaCaT Cells under Solar Spectrum. J Funct Biomater, 14(5):280. doi: 10.3390/jfb14050280. PMID: 37233390; PMCID: PMC10219309.
https://doi.org/10.3390/jfb14050280
Choi SY, Koh YG, Yoo KH, Han HS, Seok J, Kim BJ. (2024). A randomized, participant- and evaluator-blinded, matched-pair, prospective study comparing the safety and efficacy between polycaprolactone and polynucleotide fillers in the correction of crow’s feet. Chung-Ang University College of Medicine, Korea.
(No DOI available)
Financial Times. (2025). Why polynucleotides are the new Botox. Written by Hannah Coates.
https://www.ft.com/content/80093a82-e49e-425a-9098-dc51b1688e40
Heo TH, Gu BK, Ohk K, Yoon JK, Son YH, Chun HJ, Yang DH, Jeong GJ. (2025). Polynucleotide and Hyaluronic Acid Mixture for Skin Wound Dressing for Accelerated Wound Healing. Tissue Eng Regen Med, 22(4):515-526. doi: 10.1007/s13770-025-00712-1. PMID: 40009152; PMCID: PMC12122959.
https://doi.org/10.1007/s13770-025-00712-1
Jeong GJ, Ahn GR, Park SJ, Hong JY, Kim BJ. (2019). A randomized, patient/evaluator-blinded, split-face study to compare the efficacy and safety of polycaprolactone and polynucleotide fillers in the correction of crow’s feet: The latest biostimulatory dermal filler for crow’s feet. J Cosmet Dermatol. doi: 10.1111/jocd.13199.
https://doi.org/10.1111/jocd.13199
Khan A, Wang G, Zho F, Gong L, Zhang J, Qi L, Cui H. (2022). Polydeoxyribonucleotide: A promising skin anti-aging agent. Chin J Plast Reconstr Surg, 4(4):187-193. doi: 10.1016/j.cjprs.2022.09.015.
https://doi.org/10.1016/j.cjprs.2022.09.015
Kim JH, Kwon TR, Lee SE, Jang YN, Han HS, Mun SK, Kim BJ. (2020). Comparative evaluation of the effectiveness of novel hyaluronic acid-polynucleotide complex dermal filler. Sci Rep, 10(1):5127. doi: 10.1038/s41598-020-61952-w. PMID: 32198443; PMCID: PMC7083941.
https://doi.org/10.1038/s41598-020-61952-w
Kim MJ, Wan J, Oksana L, Yuliia L, Chugay O, Platonova O, Yi KH. (2024). Polynucleotide-based treatments for various facial scars including combat injuries. J Dermatol Treat, 35(1). doi: 10.1080/09546634.2024.2426626.
https://doi.org/10.1080/09546634.2024.2426626
Lee DK, Oh M, Kim MJ, Oh SM. (2024). Clinical effects of polynucleotide with hyaluronic acid intradermal injections on facial erythema: Effective redness treatment using polynucleotides. Skin Res Technol, 30(9):e70034. doi: 10.1111/srt.70034. PMID: 39258788; PMCID: PMC11388635.
https://doi.org/10.1111/srt.70034
Lee KWA, Chan KWL, Lee A, Lee CH, Wan J, Wong S, Yi KH. (2024). Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness. Int J Mol Sci, 25(15):8224. doi: 10.3390/ijms25158224. PMID: 39125793; PMCID: PMC11311621.
https://doi.org/10.3390/ijms25158224
Lee YJ, Kim HT, Lee YJ, Paik SH, Moon YS, Lee WJ, Chang SE, Lee MW, Choi JH, Jung JM, Won CH. (2022). Comparison of the effects of polynucleotide and hyaluronic acid fillers on periocular rejuvenation: a randomized, double-blind, split-face trial. J Dermatol Treat, 33(1):254-260. doi: 10.1080/09546634.2020.1748857. PMID: 32248707.
https://doi.org/10.1080/09546634.2020.1748857
Marcos-Garcés V, Molina Aguilar P, Bea Serrano C, García Bustos V, Benavent Seguí J, Ferrández Izquierdo A, Ruiz-Saurí A. (2014). Age-related dermal collagen changes during development, maturation and ageing: a morphometric and comparative study. J Anat, 225(1):98-108. doi: 10.1111/joa.12186. PMID: 24754576; PMCID: PMC4089350.
https://doi.org/10.1111/joa.12186
Park KY, Kwon HJ, Youn CS, Seo SJ, Kim MN. (2018). Treatments of infra-orbital dark circles by various etiologies. Ann Dermatol, 30(5):522-528. doi: 10.5021/ad.2018.30.5.522.
https://doi.org/10.5021/ad.2018.30.5.522
Rho NK, Han KH, Cho M, Kim HS. (2024). A survey on the cosmetic use of injectable polynucleotide: The pattern of practice among Korean Dermatologists. J Cosmet Dermatol, 23(4):1243-1252. doi: 10.1111/jocd.16125. PMID: 38093498.
https://doi.org/10.1111/jocd.16125
Ward WH, Lambreton F, Goel N, et al. (2017). Clinical Presentation and Staging of Melanoma. In: Ward WH, Farma JM, editors. Cutaneous Melanoma: Etiology and Therapy [Internet]. Brisbane (AU): Codon Publications. TABLE 1, Fitzpatrick Classification of Skin Types I through VI. doi: 10.15586/codon.cutaneousmelanoma.2017.ch6.
https://www.ncbi.nlm.nih.gov/books/NBK481857/table/chapter6.t1/
YJ Lee, HT Kim, YJ Lee, SH Paik, YS Moon, WJ Lee, SE Chang, MW Lee, JH Choi, JM Jung, CH Won. (2023). Current practices and perceived effectiveness of polynucleotides for treatment of facial erythema by cosmetic physicians. Skin Res Technol. doi: 10.1111/srt.13466.
https://doi.org/10.1111/srt.13466
Last reviewed: August 2025
Next scheduled update: August 2026
