What Is Rejuran? Understanding Salmon DNA Skin Treatments
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18 min read
Updated On
Dec 16, 2025

What Is Rejuran? Understanding Salmon DNA Skin Treatments

Heart aesthetics hobart team

Written by

Heart Aesthetics Hobart Team

Georgie Kurzyp, BSN, RN

Medically reviewed by

Georgie Kurzyp, BSN, RN

Rejuran is part of a new generation of skin therapies that focus less on appearance and more on supporting function. Using polynucleotides from salmon DNA, this treatment aims to assist the skin’s own repair processes after time, stress or environmental exposure.

Developed in South Korea and now used in clinics across Australia, Rejuran is one option for people who wish to support elasticity, hydration and resilience without adding volume. In Hobart, it is offered within Cosmetic Aesthetics consultations, including for those with sensitive or previously compromised skin.

Rejuran under-eye care image from a Hobart clinic showing delicate area hydration.
Rejuran salmon DNA skin therapy in Hobart to support collagen, texture and barrier strength over time.

Quick Answers About Rejuran Skin Rejuvenation

What is Rejuran and how does it work?
Rejuran is a skin therapy that uses polynucleotides derived from salmon DNA to support skin repair processes. It is placed into the dermis, where it may help the skin repair damaged tissue, support collagen networks and maintain elasticity over time.

What results can I expect after Rejuran treatments?
Some people report changes in hydration, texture and elasticity in the weeks after a treatment course. Any improvement, if it occurs, usually develops gradually over time and varies between individuals.

Is Rejuran available in Hobart?
Yes. In Hobart, Rejuran-based skin therapies are offered at Heart Aesthetics Hobart as part of a Cosmetic Aesthetics consultation, where plans are developed after an assessment of your skin, goals and medical history.

Rejuran acne-scar support education image from a Hobart cosmetic clinic.
Polynucleotide Rejuran treatments in Australia for skin that feels dull, dry or stressed by the environment.

How Rejuran Supports Skin Repair

What makes Rejuran different from many traditional skin treatments is its focus on biological repair rather than surface cosmetic change. It doesn’t rely on synthetic volume or surface hydration. Instead, it delivers biocompatible polynucleotides from salmon DNA into the deeper layers of the skin, where they are intended to support normal cell function.

These polynucleotides are long-chain molecules that are designed to be biocompatible. Once delivered into the dermis, they may support the way the skin repairs damaged tissue, organises collagen and maintains moisture balance. Over time, this process may help with elasticity, texture and barrier strength for some people, although outcomes vary and are not guaranteed.

Why Salmon DNA?

Salmon DNA is used in Rejuran because it closely resembles human DNA in structure, and is considered compatible with skin tissue. When introduced into the skin, these polynucleotides are thought to support repair processes that typically slow down with age. This may include the way the skin heals, maintains hydration and responds to daily exposure.

The treatment is often described as working through three main pathways:

  • Supporting cellular repair responses
  • Supporting new cell growth through the regeneration of healthy skin tissue
  • Reinforcing barrier function to help protect against environmental stress

Collagen, Texture, and Skin Strength

Rejuran is thought to interact with fibroblasts, the cells responsible for producing collagen. As collagen networks are supported, some people feel that areas which once seemed thin, creased or slack become more resilient over time, with changes in firmness and surface texture that develop gradually.

For some people, fine lines may appear less noticeable as the skin structure improves. The focus is on supporting how the skin responds to everyday stress and ageing changes rather than altering facial muscle movement.

Calming, Not Just Correcting

Rejuran is often chosen for skin that feels reactive, fragile or easily irritated. Some people report changes in redness, sensitivity or irritation after a treatment course, although individual responses differ and other causes of inflammation may still need medical review.

In clinics across Australia, including Hobart, Rejuran is used to support natural repair processes that already exist in the skin. The intent is to work with your usual features, rather than to change how your face looks or feels in everyday life.

Rejuran education graphic from a Hobart cosmetic clinic on hydration and barrier care.
Rejuran S polynucleotide therapy used after assessment for acne scarring and uneven skin texture.

What Skin Concerns Can Rejuran Help With?

Rejuran is often considered for skin that has become less resilient over time, whether due to ageing, environmental stress, or slowed cellular repair. Rather than masking change, it is intended to work beneath the surface to support repair processes where the skin has lost structure, balance, or clarity.

In Hobart, many clients turn to Rejuran to seek support for early lines, firmness in the cheeks or jawline, and texture in areas affected by past breakouts, acne scarring, or sun exposure. The treatment is thought to support collagen activity and surface texture, so some people notice gradual changes in irregularities and skin strength over a course of sessions, although responses vary and outcomes are not guaranteed.

The treatment is also used to support hydration, in part by reinforcing the skin’s natural barrier. This can be particularly relevant during Tasmania’s cooler months, when dryness and reactivity are more common. Some people report that their skin holds moisture better, feels more comfortable and seems less prone to irritation after a course of treatments, although this is not universal.

Rejuran may be considered for a wide range of skin types and tones where appropriate after assessment. It can be used in oily, dry or combination skin and in Fitzpatrick skin types I through VI when deemed suitable by your practitioner. Some people consider it when noticing early signs of dullness, thinning or fatigue, while others use it alongside other measures to support recovery after stress, sun exposure or inflammation.

In Hobart and across Australia, Rejuran is often discussed as focusing on supporting skin function rather than altering facial features, by aiming to help the skin respond to daily stress and ageing changes over time.

Rejuran salmon DNA skin care education image from a Hobart cosmetic practice.
Rejuran I under-eye treatment in Hobart supporting thin, fragile skin and early creasing around the eyes.

Which Type of Rejuran Is Right for You?

Rejuran is available in three formulations that are often used for different skin concerns with targeted application. While they all involve placing polynucleotides into the skin, the areas treated and treatment pattern vary depending on the concerns identified during your assessment.

Rejuran Healer

Rejuran Healer is commonly used as a general option. It’s used across the full face and is often considered by people seeking support for skin tone, elasticity, and strength. This version is thought to support broader collagen activity and is placed at a series of points across the skin as part of a planned treatment pattern. Over time, some people report changes in fine lines, texture and overall skin comfort, although responses vary and outcomes are not guaranteed. It may be considered for people who want to address early signs of ageing or support tired-looking skin while maintaining their usual features.

Rejuran S

Rejuran S is commonly used in areas of scars. Unlike the full-face approach of Rejuran Healer, this version is used in small treatment zones and is placed into or around selected areas of old or new scarring after assessment. It’s often chosen by clients with acne scars or uneven skin from past damage. Rejuran S is thought to support tissue remodelling and collagen organisation in scarred areas, which may be associated with changes in surface texture over time for some people. Any change tends to develop gradually and will not be the same for everyone.

Rejuran I

Rejuran I focuses on the under-eye region, where skin is especially thin and sensitive. This formulation is placed carefully in small amounts to suit the delicate tissue in this area. It’s often considered for people experiencing early creasing, dark circles, or general thinning around the eyes. Rejuran I is intended to support the skin barrier in this fragile zone, and some people feel the area retains moisture better and is less reactive to daily stress after a treatment course, although results vary.

At Heart Aesthetics Hobart, each Rejuran formulation is selected after a Cosmetic Aesthetics consultation that looks at how your skin heals, moves and responds to stress. Treatment plans are customised to focus on areas that need the most support, whether it’s overall texture, scarring, or delicate zones like the under-eyes. By matching the product to your skin’s function and condition, the aim is to support your existing features rather than to change their underlying character.

How Results Develop After Rejuran Treatment

Rejuran is not a quick-fix treatment; it’s a structured process that builds progressively. In the first few weeks, some people report changes in hydration, surface texture and day-to-day irritation. Redness and reactivity may settle for some, and the skin can feel more comfortable as it adjusts, although this is not the case for everyone.

Over the next month or so, people who respond sometimes feel that their skin creases less easily and that fine lines look less obvious. The barrier may feel more robust and the skin may appear more even or refreshed, particularly in areas that previously looked tired.

Over several months, collagen support is usually discussed as a longer-term process. Some people describe changes in firmness, pore visibility or the way scars look and feel, but the degree and timing of any change differ widely between individuals, and no specific outcome can be guaranteed.

Most clients are offered three to four sessions spaced three to four weeks apart. Your practitioner may also discuss occasional review or maintenance sessions, depending on how your skin responds and your goals over time.

Rejuran skin boost education in a Hobart clinic on hydration and elasticity care.
Rejuran skin therapy combined with tailored home care to support hydration and skin-barrier function.

Supporting Skin Recovery: Rejuran Aftercare and Safety

What you do after treatment plays an important role in how your skin recovers and responds. In the hours following your session, it’s important to keep the area clean, cool, and free from friction. Avoid makeup, heavy creams, or sun exposure for the first 24 hours, and give your skin time to settle before reintroducing active products.

For the first 48 hours, skip saunas, exfoliation, and strenuous exercise. Choose gentle cleansers, layer in hydration, and apply SPF 50+ daily. This routine supports your skin’s recovery after treatment and helps reduce irritation while the treated area settles.

At Heart Aesthetics Hobart, you’ll be given a home care routine suited to your current skin condition. Products containing hyaluronic acid, vitamin C, or peptides may be recommended to support the intended effects of Rejuran and reinforce the skin barrier during healing.

Rejuran is generally well tolerated in suitable candidates after assessment of skin and medical history. Its polynucleotides are highly purified and designed to be biocompatible, but irritation, sensitivity or other reactions can still occur. Treatments at Heart Aesthetics Hobart are performed under sterile conditions using single-use equipment and clinical protocols that meet Australian safety standards.

Common short-term effects include redness, swelling or small bumps at the treatment sites, which often settle over the next one to two days, although in some people they may last longer. These effects can sometimes be eased with a cool compress if advised by your practitioner. Allergic reactions are uncommon but can occur, even with purified formulations.

Rejuran is described as a non-surgical option, but as with any cosmetic treatment there are potential risks, including delayed healing, bruising, infection or individual sensitivity. Rejuran is usually not recommended during pregnancy, while breastfeeding, or if you have active skin infections or certain autoimmune conditions, and these factors will be discussed during your consultation to assess whether treatment is suitable for you.

What to Expect During a Rejuran Session in Hobart

Every Rejuran session at Heart Aesthetics Hobart begins with a consultation that examines your skin’s condition, movement, and underlying patterns of change. This isn’t just a checklist; it’s a clinical assessment that shapes your treatment plan.

Once mapped out, your skin is cleansed, photographed, and numbed with a topical cream. Rejuran is then delivered to the planned treatment areas using techniques suited to your skin type and treatment goals. A cooling mask may follow to ease redness and support early healing.

Small, raised bumps or mild redness may appear after treatment and often settle over the next one to two days, although in some cases they can last longer. To support recovery, you will usually be advised to avoid heat, makeup or vigorous activity during the first two days.

What Does Rejuran Cost in Hobart?

In Hobart, Rejuran treatment fees are usually in the range of $650 to $1350 per session, depending on the formulation used, the areas treated and the amount of product required, and your exact fee will be confirmed during consultation.

Some people choose to plan a series of three to four sessions, and your practitioner can discuss any available course pricing, likely session numbers and possible maintenance needs with you during your appointment.

In general, cosmetic treatments like Rejuran are not covered by private health insurance, so it is important to consider the cost of treatment as part of your decision-making.

Rejuran under-eye appearance care photo from a Hobart clinic on texture and hydration.
Planned Rejuran skin booster session to support fine lines and early ageing changes

Frequently Asked Questions About Rejuran Treatments in Hobart

What are the benefits of salmon DNA treatments like Rejuran?
Rejuran is intended to support collagen repair, may help soften the appearance of fine lines, support hydration, and support the skin barrier. Some people feel it offers changes that sit naturally with tired, ageing or damaged skin, although responses vary and results are not guaranteed.

How does Rejuran Healer compare to other formulations?
Rejuran Healer is commonly used as a general option in the range. It’s used across the full face to support elasticity, fine lines, and general skin quality by aiming to support cellular repair. People who respond sometimes notice gradual changes in these areas over a treatment course, but outcomes differ between individuals.

What is Rejuran I used for?
Rejuran I targets delicate areas such as the under-eyes. It is used to support tone, the appearance of fine lines and dark circles, and the comfort of fragile skin in the tear trough region. Suitability is assessed on an individual basis.

How many Rejuran sessions will I need?
Many treatment plans involve three to four initial sessions spaced three to four weeks apart, but the number and spacing of sessions you may need depends on your skin, goals and how you respond. Maintenance every six to twelve months may be discussed to help support the effect over time, if appropriate for you.

Is Rejuran safe to use in Australia?
Rejuran is used in Australian clinical settings that follow relevant safety and infection-control standards. At Heart Aesthetics Hobart, treatments are performed using regulated medical products in a sterile, professional setting. As with any cosmetic therapy, individual risks are discussed during your consultation to help determine whether the treatment is appropriate for your skin and health.

Are there any side effects after Rejuran?
Minor swelling, redness, or raised spots at the application points can occur and often settle within 24–48 hours. In some people they may last longer and may need review if they persist. Less common side effects and allergic responses are possible, and your practitioner will discuss these with you before treatment.

Rejuran formulation discussion graphic from a Hobart clinic on salmon DNA and skin.
Rejuran Healer full-face treatment plans designed to support overall tone, elasticity and day-to-day skin comfort.

Considering Rejuran Skin Therapy in Hobart

Whether you’re looking to repair signs of ageing, calm inflammation, or restore texture after breakouts or stress, Rejuran is one non-surgical option that may support your skin from within when used in suitable candidates. Some people report that, over a course of treatment, their skin feels stronger and more even in tone, but responses vary and visible change cannot be guaranteed. The approach is generally gradual and can be planned with sensitive skin and local climate stresses in mind, focusing on the areas that concern you most. If you are considering regenerative skin therapy, you can book a Cosmetic Aesthetics consultation in Hobart to discuss whether Rejuran or other options are appropriate for you, including likely benefits, risks, costs and alternatives.

References

Heart Aesthetics Hobart always ensures the use of credible, up-to-date references for all our content related to cosmetic treatments in Hobart. We rely on peer-reviewed studies and trusted medical sources to provide accurate information to our local community in Hobart, Tasmania.

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(No DOI available)

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Last reviewed: November 2025
Next scheduled update: August 2026

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